What is the most likely site of nucleophilic attack on cyclohexanone?

 

Axial Face
of Carbonyl
Carbon

 
 

 


Cyclohexanone – perspective view

 

Equatorial
Face of
Carbonyl
Carbon

 
 

 


 

 

Electron density maps of molecular orbitals:

 

Cyclohexanone – Equatorial Face (Blue = greatest electron deficiency)

 

 

Cyclohexanone – Axial Face (Blue = greatest electron deficiency)