What is the most likely site of nucleophilic attack on
cyclohexanone?
Axial Face
of Carbonyl
Carbon
|
|
Cyclohexanone – perspective view
Equatorial
Face of
Carbonyl
Carbon
|
|
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Electron
density maps of molecular orbitals:
Cyclohexanone – Equatorial Face (Blue = greatest electron
deficiency)


Cyclohexanone – Axial Face (Blue = greatest electron
deficiency)

